Regulations last checked for updates: Sep 12, 2025

Title 21 - Food and Drugs last revised: Sep 04, 2025
§ 528.2000 - Deletion of exon 7 of CD163 gene in domestic pigs.

(a) Specifications. Deletion of one (heterozygous) or two (homozygous) copies of exon 7 of CD163 gene1(abbreviated CD163ΔE7) in domestic pigs (Sus scrofa domesticus).

(b) Sponsor. See No. 086205 in § 510.600(c) of this chapter.

(c) Conditions of use—(1) Intended use. Deletion of exon 7 of the CD163 gene in domestic pigs (Sus scrofa domesticus) is intended to confer resistance to porcine reproductive and respiratory syndrome virus (PRRSV) in homozygous pigs. Pigs carrying one or two copies of CD163DE7, and their offspring, are intended for breeding or to be used as sources of food.

[90 FR 40970, Aug. 22, 2025]
authority: 21 U.S.C. 360b.
source: 74 FR 6823, Feb. 11, 2009, unless otherwise noted.
cite as: 21 CFR 528.2000