21 CFR 112.180 - Under what circumstances may FDA modify or revoke an approved variance?

Regulations last checked for updates: Feb 12, 2026

Title 21 - Food and Drugs last revised: Dec 18, 2026

View all text of Subpart P [§ 112.171 - § 112.182]

§ 112.180 - Under what circumstances may FDA modify or revoke an approved variance?

We may modify or revoke a variance if we determine that such variance is not reasonably likely to ensure that the produce is not adulterated under section 402 of the Federal Food, Drug, and Cosmetic Act and to provide the same level of public health protection as the requirements of this part.

authority: 21 U.S.C. 321,331,342,350h,371; 42 U.S.C. 243,264,271

source: 80 FR 74547, Nov. 27, 2015, unless otherwise noted.

cite as: 21 CFR 112.180