Pub. L. 119–60, div. F, title LXIV, § 6404(c)(2), (d), (g), Dec. 18, 2025, 139 Stat. 1618, provided that, effective 180 days after Dec. 18, 2025, section is amended as follows:

(1) in the heading, by striking “National Counterproliferation and Biosecurity Center” and inserting “Counterproliferation and Biosecurity”;

(2) in subsection (a)—

(A) in the heading, by striking “Establishment” and inserting “Organization”;

(B) in paragraph (1)—

(i) by striking “The President shall establish a National Counterproliferation and Biosecurity Center, taking into account all appropriate government tools to” and inserting “The Director of National Intelligence shall”; and

(ii) in subparagraph (A), by inserting “support efforts to” before “prevent and halt”;

(C) by striking paragraph (2) and inserting the following:

“(2) The Director of National Intelligence shall appoint an appropriate official within the Office of the Director of National Intelligence to oversee the efforts and activities undertaken pursuant to this section.”; and

(D) by striking paragraphs (3) and (4); and

(3) in subsection (b)—

(A) in paragraph (1)—

(i) by striking “establishing the National Counterproliferation and Biosecurity Center, the President” and inserting “carrying out this section, the Director”; and

(ii) in subparagraph (A), by striking “Establishing a primary organization within the United States Government for integrating” and inserting “Integrating”; and

(B) in paragraph (2), by striking “In establishing the National Counterproliferation and Biosecurity Center, the President shall address the following missions and objectives to ensure that the Center serves as the lead for the intelligence community for” and inserting “In carrying out this section, the Director shall address the following missions and objectives to ensure”; and

(4) by striking subsections (c), (d), and (e).

See 2025 Amendment notes below.

This chapter, referred to in subsec. (d)(1), was in the original “this Act”, meaning act July 26, 1947, ch. 343, 61 Stat. 495, known as the National Security Act of 1947, which is classified principally to this chapter. For complete classification of this Act to the Code, see Tables.

The Executive Order in February 2004 establishing the President’s Commission on Weapons of Mass Destruction, referred to in subsec. (d)(1), is Ex. Ord. No. 13328, Feb. 6, 2004, 69 F.R. 6901, which was revoked by Ex. Ord. No. 13385, § 3(a), Sept. 29, 2005, 70 F.R. 57990, and was formerly set out as a note under section 2301 of this title.

Section was formerly classified to section 404o–1 of this title prior to editorial reclassification and renumbering as this section.

2025—Pub. L. 119–60, § 6404(c)(2)(A), substituted “Counterproliferation and Biosecurity” for “National Counterproliferation and Biosecurity Center” in section catchline.

Subsec. (a). Pub. L. 119–60, § 6404(c)(2)(B)(i), substituted “Organization” for “Establishment” in heading.

Subsec. (a)(1). Pub. L. 119–60, § 6404(c)(2)(B)(ii)(I), substituted “The Director of National Intelligence shall” for “The President shall establish a National Counterproliferation and Biosecurity Center, taking into account all appropriate government tools to” in introductory provisions.

Subsec. (a)(1)(A). Pub. L. 119–60, § 6404(c)(2)(B)(ii)(II), inserted “support efforts to” before “prevent and halt”.

Subsec. (a)(2). Pub. L. 119–60, § 6404(c)(2)(B)(iii), added par. (2) and struck out former par. (2) which read as follows: “The head of the National Counterproliferation and Biosecurity Center shall be the Director of the National Counterproliferation and Biosecurity Center, who shall be appointed by the Director of National Intelligence.”

Subsec. (a)(3), (4). Pub. L. 119–60, § 6404(c)(2)(B)(iv), struck out pars. (3) and (4) which read as follows:

“(3) The National Counterproliferation and Biosecurity Center shall be located within the Office of the Director of National Intelligence.

“(4) The Director of the National Counterproliferation and Biosecurity Center shall serve as the principal coordinator for the intelligence community, and as the principal advisor to the Director of National Intelligence, with respect to counterproliferation, biosecurity, and foreign biological threats.”

Subsec. (b)(1). Pub. L. 119–60, § 6404(c)(2)(C)(i)(I), substituted “carrying out this section, the Director” for “establishing the National Counterproliferation and Biosecurity Center, the President” in introductory provisions.

Subsec. (b)(1)(A). Pub. L. 119–60, § 6404(c)(2)(C)(i)(II), substituted “Integrating” for “Establishing a primary organization within the United States Government for integrating”.

Subsec. (b)(2). Pub. L. 119–60, § 6404(c)(2)(C)(ii), substituted “In carrying out this section, the Director shall address the following missions and objectives to ensure” for “In establishing the National Counterproliferation and Biosecurity Center, the President shall address the following missions and objectives to ensure that the Center serves as the lead for the intelligence community for” in introductory provisions.

Subsecs. (c) to (e). Pub. L. 119–60, § 6404(d), struck out subsecs. (c) to (e) which related to national security waiver, report to Congress, and sense of Congress, respectively.

2024—Subsec. (a)(4). Pub. L. 118–159, § 6502(1), substituted “counterproliferation, biosecurity, and” for “biosecurity and”.

Subsec. (b)(1)(A). Pub. L. 118–159, § 6502(2)(A)(i), struck out “analyzing and” before “integrating all intelligence”.

Subsec. (b)(1)(C). Pub. L. 118–159, § 6502(2)(A)(ii), substituted “Coordinating the establishment of” for “Establishing”.

Subsec. (b)(1)(D). Pub. L. 118–159, § 6502(2)(A)(iii), substituted “Overseeing the dissemination of” for “Disseminating”.

Subsec. (b)(1)(E). Pub. L. 118–159, § 6502(2)(A)(iv), inserted “and coordinating” after “Conducting”.

Subsec. (b)(1)(G). Pub. L. 118–159, § 6502(2)(A)(v), substituted “Coordinating and advancing” for “Conducting”.

Subsec. (b)(2)(B). Pub. L. 118–159, § 6502(2)(B)(i), struck out “and analysis” after “coordinating the collection”.

Subsec. (b)(2)(C). Pub. L. 118–159, § 6502(2)(B)(iii), added subpar. (C). Former subpar. (C) redesignated (D).

Subsec. (b)(2)(D). Pub. L. 118–159, § 6502(2)(B)(ii), (iv), redesignated subpar. (C) as (D) and inserted “on matters relating to biosecurity and foreign biological threats” after “public health”. Former subpar. (D) redesignated (E).

Subsec. (b)(2)(E). Pub. L. 118–159, § 6502(2)(B)(ii), redesignated subpar. (D) as (E). Former subpar. (E) redesignated (F).

Subsec. (b)(2)(F). Pub. L. 118–159, § 6502(2)(B)(v), which directed insertion of “and authorities” after “capabilities”, was executed by making the insertion after “capabilities” the second place appearing, to reflect the probable intent of Congress.

Pub. L. 118–159, § 6502(2)(B)(ii), redesignated subpar. (E) as (F).

Subsec. (b)(2)(G). Pub. L. 118–159, § 6502(2)(B)(vi), added subpar. (G).

2022—Pub. L. 117–103, § 401(a), (d), substituted “Counterproliferation and Biosecurity” for “Counter Proliferation” in section catchline and “National Counterproliferation and Biosecurity Center” for “National Counter Proliferation Center” and “counterproliferation” for “counter proliferation” wherever appearing in text.

Subsec. (a)(1). Pub. L. 117–103, § 401(b)(1), inserted dash after “government tools to” and subpar. (A) designation before “prevent” and added subpar. (B).

Subsec. (a)(4). Pub. L. 117–103, § 401(b)(2), added par. (4).

Subsec. (b). Pub. L. 117–103, § 401(c), designated introductory provisions as par. (1) and inserted heading, redesignated former pars. (1) to (7) as subpars. (A) to (G), respectively, of par. (1) and realigned margins, and added par. (2).

2010—Subsec. (a). Pub. L. 111–259 designated existing provisions as par. (1), substituted “The” for “Not later than 18 months after December 17, 2004, the”, and added pars. (2) and (3).

Amendment by Pub. L. 119–60 effective 180 days after Dec. 18, 2025, see section 6404(g) of Pub. L. 119–60, set out as a note under section 3025 of this title.

For Determination by President that section take effect on Apr. 21, 2005, see Memorandum of President of the United States, Apr. 21, 2005, 70 F.R. 23925, set out as a note under section 3001 of this title.

Section effective not later than six months after Dec. 17, 2004, except as otherwise expressly provided, see section 1097(a) of Pub. L. 108–458, set out in an Effective Date of 2004 Amendment; Transition Provisions note under section 3001 of this title.

Pub. L. 119–60, div. F, title LXIV, § 6404(a), Dec. 18, 2025, 139 Stat. 1617, provided that:

Pub. L. 119–60, div. F, title LXIV, § 6404(h), Dec. 18, 2025, 139 Stat. 1618, provided that: “On and after the date that is 180 days after the date of enactment of this Act [Dec. 18, 2025], any reference to the National Counterproliferation and Biosecurity Center in law shall be treated as a reference to the Office of the Director of National Intelligence, and any reference to the Director of the National Counterproliferation and Biosecurity Center in law shall be treated as a reference to the Director of National Intelligence.”

Pub. L. 117–103, div. X, title IV, § 401(e), Mar. 15, 2022, 136 Stat. 975, provided that: “Any reference in any law, regulation, guidance, instruction, or other document of the United States Government to the National Counter Proliferation Center shall be deemed to refer to the National Counterproliferation and Biosecurity Center.”

Reporting functions of President under this section assigned to the Director of National Intelligence by section 3 of Memorandum of President of the United States, Apr. 21, 2005, 70 F.R. 48633, set out as a note under section 301 of Title 3, The President.