A prior section 280b–1, act July 1, 1944, ch. 373, title III, § 392, as added Pub. L. 99–649, § 3, Nov. 10, 1986, 100 Stat. 3634; amended Pub. L. 101–558, § 2(b), Nov. 15, 1990, 104 Stat. 2772; Pub. L. 102–531, title III, §§ 301, 312(d)(4), Oct. 27, 1992, 106 Stat. 3482, 3504; Pub. L. 103–183, title II, § 203(a)(2), (b)(1), Dec. 14, 1993, 107 Stat. 2232, which related to prevention and control activities, was transferred to section 280b–0 of this title.

Another prior section 280b–1, act July 1, 1944, ch. 373, title III, § 391, as added Oct. 22, 1965, Pub. L. 89–291, § 2, 79 Stat. 1059; amended Mar. 13, 1970, Pub. L. 91–212, § 10(b)(3), 84 Stat. 66; July 23, 1974, Pub. L. 93–353, title II, § 202(b), 88 Stat. 372, defined “sciences related to health”, “National Medical Libraries Assistance Advisory Board”, “Board”, and “medical library”, prior to repeal by Pub. L. 99–158, § 3(b), Nov. 20, 1985, 99 Stat. 879.

2025—Subsec. (a)(2)(C). Pub. L. 119–44, § 103(a)(1)(A), inserted “and associated risks” before period at end.

Subsec. (a)(2)(D). Pub. L. 119–44, § 103(a)(1)(B), substituted “substances causing overdose” for “opioids”.

Subsec. (a)(3). Pub. L. 119–44, § 103(b)(1), substituted “and Indian Tribes for the following purposes:” for “and Indian Tribes—” in introductory provisions.

Subsec. (a)(3)(A). Pub. L. 119–44, § 103(b)(2), amended subpar. (A) generally. Prior to amendment, subpar. (A) read as follows: “to carry out innovative projects for grantees to rapidly respond to controlled substance misuse, abuse, and overdoses, including changes in patterns of controlled substance use; and”.

Subsec. (a)(3)(B). Pub. L. 119–44, § 103(b)(3), substituted “For any” for “for any”.

Subsec. (b)(2)(B). Pub. L. 119–44, § 103(a)(2)(A), inserted “, and associated risk factors,” after “such overdoses”.

Subsec. (b)(2)(C). Pub. L. 119–44, § 103(a)(2)(B), substituted “monitoring and identifying” for “coding”.

Subsec. (b)(2)(E). Pub. L. 119–44, § 103(a)(2)(C), inserted a comma after “public health laboratories” and “and other emerging substances related” after “analogues”.

Subsec. (b)(2)(F). Pub. L. 119–44, § 103(a)(2)(D), inserted “and associated risk factors” after “overdoses”.

Subsec. (e). Pub. L. 119–44, § 103(c), substituted “$505,579,000 for each of fiscal years 2026 through 2030” for “$496,000,000 for each of fiscal years 2019 through 2023”.

2022—Subsecs. (a)(1)(B), (C), (b)(1)(B), (C). Pub. L. 117–328, § 1271(b)(2), substituted “Indian Tribes” for “Indian tribes”.

Subsecs. (c) to (e). Pub. L. 117–328, § 1271(b)(1), added subsec. (c) and redesignated former subsecs. (c) and (d) as (d) and (e), respectively.